The Marvel Universe made 2000 years ago in the Roman Empire:

Captain America, Deadpool, Ghost Rider, Iron Man, Black Widow, Blade, Daredevil, Doctor Strange, Elektra, Falcon, Hawkeye, Luke Cage, Moon Knight, Morbius, Punisher, Thor, Scarlet Witch, Silver Surfer, Spider-Man, hulk

Clearly the female characters look more like the Middle Ages than the Roman Empire;

Thor didn’t change much for obvious reasons as the Hulk is basically the Planet Hulk version.

More colorful characters like Daredevil and Hawkeye differ a little